diff --git a/Library/Homebrew/env_config.rb b/Library/Homebrew/env_config.rb
index f658da479e..233decbdf9 100644
--- a/Library/Homebrew/env_config.rb
+++ b/Library/Homebrew/env_config.rb
@@ -38,6 +38,18 @@ module Homebrew
                      "A no-op when using Homebrew's vendored, relocatable Ruby on macOS (as it doesn't work).",
         boolean:     true,
       },
+      HOMEBREW_BOTTLE_DOMAIN:                 {
+        description:  "Use this URL as the download mirror for bottles. " \
+                      "If bottles at that URL are temporarily unavailable, " \
+                      "the default bottle domain will be used as a fallback mirror. " \
+                      "For example, `HOMEBREW_BOTTLE_DOMAIN=http://localhost:8080` will cause all bottles to " \
+                      "download from the prefix `http://localhost:8080/`. " \
+                      "If bottles are not available at `HOMEBREW_BOTTLE_DOMAIN` " \
+                      "they will be downloaded from the default bottle domain.",
+        default_text: "macOS: `https://ghcr.io/v2/homebrew/core`, " \
+                      "Linux: `https://ghcr.io/v2/linuxbrew/core`.",
+        default:      HOMEBREW_BOTTLE_DEFAULT_DOMAIN,
+      },
       HOMEBREW_BREW_GIT_REMOTE:               {
         description: "Use this URL as the Homebrew/brew `git`(1) remote.",
         default:     HOMEBREW_BREW_DEFAULT_GIT_REMOTE,
diff --git a/Library/Homebrew/software_spec.rb b/Library/Homebrew/software_spec.rb
index d6885aa4b7..0147c2e0d7 100644
--- a/Library/Homebrew/software_spec.rb
+++ b/Library/Homebrew/software_spec.rb
@@ -297,7 +297,7 @@ class Bottle
   attr_reader :name, :resource, :prefix, :cellar, :rebuild
 
   def_delegators :resource, :url, :verify_download_integrity
-  def_delegators :resource, :cached_download, :fetch
+  def_delegators :resource, :cached_download
 
   def initialize(formula, spec, tag = nil)
     @name = formula.name
@@ -324,6 +324,15 @@ class Bottle
     root_url(spec.root_url, spec.root_url_specs)
   end
 
+  def fetch(verify_download_integrity: true)
+    @resource.fetch(verify_download_integrity: verify_download_integrity)
+  rescue DownloadError
+    raise unless fallback_on_error
+
+    fetch_tab
+    retry
+  end
+
   def clear_cache
     @resource.clear_cache
     github_packages_manifest_resource&.clear_cache
@@ -427,6 +436,19 @@ class Bottle
     specs
   end
 
+  def fallback_on_error
+    # Use the default bottle domain as a fallback mirror
+    if @resource.url.start_with?(Homebrew::EnvConfig.bottle_domain) &&
+       Homebrew::EnvConfig.bottle_domain != HOMEBREW_BOTTLE_DEFAULT_DOMAIN
+      opoo "Bottle missing, falling back to the default domain..."
+      root_url(HOMEBREW_BOTTLE_DEFAULT_DOMAIN)
+      @github_packages_manifest_resource = nil
+      true
+    else
+      false
+    end
+  end
+
   def root_url(val = nil, specs = {})
     return @root_url if val.nil?
 
@@ -457,7 +479,11 @@ class BottleSpecification
 
   def root_url(var = nil, specs = {})
     if var.nil?
-      @root_url ||= HOMEBREW_BOTTLE_DEFAULT_DOMAIN
+      @root_url ||= if (github_packages_url = GitHubPackages.root_url_if_match(Homebrew::EnvConfig.bottle_domain))
+        github_packages_url
+      else
+        Homebrew::EnvConfig.bottle_domain
+      end
     else
       @root_url = if (github_packages_url = GitHubPackages.root_url_if_match(var))
         github_packages_url
diff --git a/Library/Homebrew/sorbet/rbi/hidden-definitions/hidden.rbi b/Library/Homebrew/sorbet/rbi/hidden-definitions/hidden.rbi
index 3002e458ba..0950035dc5 100644
--- a/Library/Homebrew/sorbet/rbi/hidden-definitions/hidden.rbi
+++ b/Library/Homebrew/sorbet/rbi/hidden-definitions/hidden.rbi
@@ -8331,6 +8331,8 @@ module Homebrew::EnvConfig
 
   def self.bootsnap?(); end
 
+  def self.bottle_domain(); end
+
   def self.brew_git_remote(); end
 
   def self.browser(); end
diff --git a/docs/Manpage.md b/docs/Manpage.md
index 89eefb2c66..fdec00d5c3 100644
--- a/docs/Manpage.md
+++ b/docs/Manpage.md
@@ -1878,6 +1878,11 @@ example, run `export HOMEBREW_NO_INSECURE_REDIRECT=1` rather than just
 - `HOMEBREW_BOOTSNAP`
   <br>If set, use Bootsnap to speed up repeated `brew` calls. A no-op when using Homebrew's vendored, relocatable Ruby on macOS (as it doesn't work).
 
+- `HOMEBREW_BOTTLE_DOMAIN`
+  <br>Use this URL as the download mirror for bottles. If bottles at that URL are temporarily unavailable, the default bottle domain will be used as a fallback mirror. For example, `HOMEBREW_BOTTLE_DOMAIN=http://localhost:8080` will cause all bottles to download from the prefix `http://localhost:8080/`. If bottles are not available at `HOMEBREW_BOTTLE_DOMAIN` they will be downloaded from the default bottle domain.
+
+  *Default:* macOS: `https://ghcr.io/v2/homebrew/core`, Linux: `https://ghcr.io/v2/linuxbrew/core`.
+
 - `HOMEBREW_BREW_GIT_REMOTE`
   <br>Use this URL as the Homebrew/brew `git`(1) remote.
 
diff --git a/manpages/brew.1 b/manpages/brew.1
index 850fbaea4a..f53def03a8 100644
--- a/manpages/brew.1
+++ b/manpages/brew.1
@@ -2644,6 +2644,15 @@ Use this as the \fBbat\fR configuration file\.
 If set, use Bootsnap to speed up repeated \fBbrew\fR calls\. A no\-op when using Homebrew\'s vendored, relocatable Ruby on macOS (as it doesn\'t work)\.
 .
 .TP
+\fBHOMEBREW_BOTTLE_DOMAIN\fR
+.
+.br
+Use this URL as the download mirror for bottles\. If bottles at that URL are temporarily unavailable, the default bottle domain will be used as a fallback mirror\. For example, \fBHOMEBREW_BOTTLE_DOMAIN=http://localhost:8080\fR will cause all bottles to download from the prefix \fBhttp://localhost:8080/\fR\. If bottles are not available at \fBHOMEBREW_BOTTLE_DOMAIN\fR they will be downloaded from the default bottle domain\.
+.
+.IP
+\fIDefault:\fR macOS: \fBhttps://ghcr\.io/v2/homebrew/core\fR, Linux: \fBhttps://ghcr\.io/v2/linuxbrew/core\fR\.
+.
+.TP
 \fBHOMEBREW_BREW_GIT_REMOTE\fR
 .
 .br